LECZENIE ŻYWIENIOWE CHOREJ Z ZAPALENIEM JELITA GRUBEGO JAKO POWIKŁANIEM PO RADIOTERAPII I CHIRURGII RAKA ODBYTNICY |
Stanisław Głuszek, Sylwia Zagórska, Bartłomiej Kotucha
Słowa kluczowe: rak odbytnicy, napromienianie, zakażenie Clostridium difficile. The purpose of this study is to present the case of 48-year woman suffering from rectal carcinoma (T3N0M0) with severe complication of preoperative radiotherapy. The patient received short course of irradiation (5 x 5 Gy) before anterior rectal resection had been performed. In 16-th day after surgery the woman presented post radiation colitis with remarkable mucosal edema leading to digestive tract obstruction. The patient was administrated total parenteral nutrition (TPN), antibiotics and anti-inflammatory drugs. In 25 day after surgery she had to be operated, because of total colon occlusion - the cecostomy was performed. In 36-th day patient's general condition had stabilized, abdominal discomfort disappeared, tolerance of diet meals was good. After that, woman had been dismissed from hospital. 3 weeks later patient was rehospitalised because of abdominal pain accompanied by diarrhea and general weakness. Colonoscopy revealed small inflammatory mucosal lesion. The Clostridium difficile was cultured in feces inoculation - patient received guided antibiotic therapy. The conservative treatment resulted in regression of pathological symptoms within 2 weeks. The diet with exclusion of gluten had been gradually administrated. In 64-th day after first operation patient was dismissed from hospital. Disturbances which occurred in patient's case were likely associated with preoperative radiotherapy. Intraoperative examination revealed long sigmoid loop located in the area of irradiation in minor pelvis. Anterior resection syndrome and post radiation colitis complicated by digestive tract patency disturbances and Clostridium difficile infection led to severe alimentary dysfunction. Key words: rectal carcinoma, irradiation, Clostridium difficile infection.
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